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Hand, foot and mouth disease – you might have heard about this virus before. But what is it and how should it be treated? Le Bonheur Pediatrician answers some common questions.

What does hand, foot and mouth disease look like?

Hand, foot, and mouth (HFM) disease usually consists of fever with painful blisters that form in or around the mouth and on the hands, feet and sometimes on the buttocks and genitals. It is most common in infants and young children, but people of any age can get this.

What causes HFM disease?

HFM disease is caused by a virus. There are a few viruses that cause HFM disease, and most belong to the genus Enterovirus.

How long does it last?

Fever may last a day or two, but the rash often takes seven to ten days to resolve. Often, the resolution of the rash is associated with peeling skin and nail changes.  In general, once the fever has resolved and the rash is no longer progressing for about 24 hours, kids may return to school.

What is the treatment for HFM disease?

This infection resolves on its own and does not require any specific treatment. Acetaminophen and ibuprofen can help reduce fever, sore throat, and pain associated with blisters. If the blisters on the palms of the hands and soles of the feet are associated with burning, ice packs may help. Benadryl may also help alleviate burning or itching associated with the blisters. Emollients are helpful for peeling skin, and popsicles may help with throat pain.  “Magic Mouthwash” can be made by mixing liquid Benadryl and Maalox in equal parts. This mouthwash can be used to lightly coat mouth sores.

When should I see my doctor?

Most of the time, if the illness is mild enough, it can be managed at home. However, if your child does not seem to be drinking enough fluids and the number of wet diapers has decreased substantially, you may need to see your doctor to check for dehydration.  Also, rarely, a secondary skin infection may develop at the site of the blisters that may require antibiotic treatment.

Where can I read more about HFM disease?

 is a great website that includes more information about this disease and other common childhood illnesses.